The Hong Kong cryptocurrency exchange Bitfinex adds support for margin trading in Ripple (XRP), NEO and Santiment (SAN).
— Bitfinex (@bitfinex) 18 сентября 2017 г.
Margin trading is enabled on RP/USD, XRP/BTC, NEO/USD, NEO/BTC, NEO/ETH, SAN/USD, SAN/BTC and SAN/ETH pairs.
List of cryptocurrency exchanges on coinhills.com
As shown, the Bitfinex exchange is the world's third largest in terms of daily trading volume, behind only the Japanese bitFlyer and the South Korean bithumb, according to the data provided by coinhills.com.
It's also noteworthy, that recently Poloniex, one of the biggest and most influential cryptocurrency exchanges, announced adding support for GAS tokens, which is the fuel token for the realization of NEO network resource control.